Investigating SAM-e for Depression
نویسنده
چکیده
For more than eight years, Richard P. Brown, M.D., associate professor of clinical psychiatry at Columbia University College of Physicians and Surgeons, has used the natural dietary supplement S-adenosylmethionine (SAM-e) to treat more than an estimated 400 patients suffering from depression, many of whom were treatment-resistant. This month, Brown is scheduled to discuss SAM-e at the American Psychiatric Association's annual meeting in New Orleans.
منابع مشابه
S-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS
BACKGROUND This study reports on clinical data from an 8-week open-label study of 20 HIV-seropositive individuals, diagnosed with Major Depressive Disorder (DSM-IV), who were treated with SAM-e (S-Adenosylmethionine). SAM-e may be a treatment alternative for the management of depression in a population reluctant to add another "pill" or another set of related side effects to an already complex ...
متن کاملCerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine.
Cerebrospinal fluid (CSF) S-adenosylmethionine (SAM) levels were significantly lower in severely depressed patients than in a neurological control group. The administration of SAM either intravenously or orally is associated with a significant rise of CSF SAM, indicating that it crosses the blood-brain barrier in humans. These observations provide a rational basis for the antidepressant effect ...
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The primary objective of this pilot clinical trial was to evaluate the effects of UP165 (derived from Zea mays L., commonly known as corn) over time. The secondary objective was the comparison for outcomes versusS-adenosyl-methionine (SAM-e). Subjects with mild depression or anxiety were given the Beck Depression Inventory second edition (BDI-II), the Beck Anxiety Inventory (BAI), and the Schwa...
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This research was performed with the objective of evaluating the accuracy of spectral angle mapper (SAM) classification using different reference spectra. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) digital images were applied in the SAM classification in order to map the distribution of hydrothermally altered rocks in the Kerman Cenozoic magmatic arc (KCMA), Iran...
متن کاملComplementary and alternative medicine for the treatment of major depressive disorder.
OBJECTIVE To review the clinical evidence supporting complementary and alternative medicine interventions for treating major depressive disorder. QUALITY OF EVIDENCE PubMed was searched from January 1966 to February 2010 using the term depressive disorder in combination with St John's wort, S-adenosylmethionine (SAM-e), exercise, acupuncture, omega-3 fatty acids, and folate. Only relevant hum...
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تاریخ انتشار 2017